The Metabolism of Bile Acids

Cover The Metabolism of Bile Acids
The Metabolism of Bile Acids
Marjorie Greene Foster
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55 2. 69 2. 58 3. 30 Hb. 120 per cent. R. B. C. 7, 895, 000. Before collection: 3 gm. Of cholic acid in capsule.
Before collection: 0. 75 gm. Of tau- rine in 25 cc. Of salt solution in- travenously.
Before collection: 2. 6 gm. Of mix- ture I cholic acid, 1 taurine in capsule.
Before collection: 3 gm. Of tau- rocholic acid in capsule. Hb. 120 per cent. R. B. C. 7, 300, 000.
" 31 Apr. 1 2 " 3 4 " 5 " 6 * This dog was kept on a diet of 75 gm. Of cane sugar and 75 gm. Of glucose during this entire
...experiment, as well as during the fore-period of 12 days.
ously does not in any way influence the output of bile acids. This is true during fasting periods as well as for full diets.
Taurocholic acid by mouth is known to be a cholagogue and this 388 Metabolism of Bile Acids. Ill action is well shown in our experiments. About 40 to 50 per cent of the taurocholic acid is excreted in the bile during the 6 hour collection period. There may have been slight delay in excretion owing to the use of capsules rather than solutions.


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