A Laboratory Guide in Pharmacology

Cover A Laboratory Guide in Pharmacology
A Laboratory Guide in Pharmacology
Torald Hermann Sollmann
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Lumen nearly obliterated; vessels constricted. The spasm is relieved by intra- venous injection of nicotin, atropin, or nitrites (Hirschfelder, 191 5, Jour. Amer. Med. Assoc, 65, 516).
Questions (a) Describe the effect of stimulating the intestine by pinching.
(b) Would this reflex be useful for the propulsion of the contents? Why?
(c) What is the effect of physostigmin?
(d) Of barium?
(e) Of atropin? (/) Of pilocarpin? (g) Of pituitary?
(h) Which of the peristaltic stimulants are neutralized b
...y atropin? (i) How is it shown that nicotin paralyzes ganglia?
EXERCISE II. ~(OPTIONAL) OBSERVATION OF PERISTALSIS ON UNOPERATED RABBIT Clip the hair from the abdomen of a rabbit which has been well fed two hours before. Observe the normal peristalsis through the intact abdominal walls. Note the effects of a sudden noise; of ammonia inhalation; of strongly pinching the skin over abdomen; of hypodermic administration of nicotin, 10 mg. Per kg. ; then of atropin, 5 mg. Per kg. (J. Auer, 1907, Proc.


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