Acute Poliomyelitis (Heine-Medin's Disease)

Cover Acute Poliomyelitis (Heine-Medin's Disease)
Acute Poliomyelitis (Heine-Medin's Disease)
Ivar Wickman
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Miiller).
Recently, Ed. Miiller established the fact that leukopenia is tolerably characteristic of the initial stage of Heine-Medin's dis- ease. He reported that in no instance either among fifteen cases in man, or among a series of infected monkeys, had he found an increase in the number of leucocytes during the febrile period.
In the minority of the cases the count was normal, but in the ma- jority only 3,000-5,000 leucocytes were present. Muller also proved that in monkeys leukopenia may oc
...cur long before the appearance of the paralysis and even in cases which remain free from paralysis. Krause, also, in such cases found leukopenia with a slight increase of lymphocytes. On the other hand, during a New York epidemic in six cases, leukocytosis ranging from 13,400 to 20,600 was reported. If further investigations confirm Miiller's observations, the leucocyte count will prove a valuable aid in differential diagnosis.
In an epidemic the character of the initial symptoms may pre- sent much variety.


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