Added Resolution Elements in Tandem Mass Spectrometry for Chemical Analysis

Cover Added Resolution Elements in Tandem Mass Spectrometry for Chemical Analysis
Added Resolution Elements in Tandem Mass Spectrometry for Chemical Analysis
Fetterolf, Dean Donald
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For TCP, the loss of HC1 from the CI molecular ion at m/z 196 to form m/z 160 was monitored. In the case of HCB the only daughter ion observed from the CI molecular ion at 284" was 35 C1~ .
The ion energy and pressure can rapidly be optimized by varying these parameters with HCB or TCP in a batch inlet or by repeated injections on the short column. The effect of ion energy on the sensitivity for HCB is shown in Figure 42, in which equal amounts of HCB were injected on the short GC column at sev
...eral different ion energies.
This method of optimization requires less than 10 minutes.
147 1001 50 96 M" 20 (M-HCI)" 160 cr 35 40 ■#- 60 140 m/z 160 180 200 tr 100-r 50 284 M~ CI" 35 ->y 20 40 60 240 m/z 260 280 300 Figure 41. Negative ion daughter spectra of phenol; (b) Hexachlorobenzene .
(a] Trichloro- 148 r& -m .3*.
3* *sx -*t rO uj _(M ^ o o o m A1ISN31NI 3AI1V13H o 149 Sample Preparation A major concern in trace analysis is the possibility of contamination of solutions (samples, reagents, and blanks) and apparatus (glassware, syringes, and the instrument itself).


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