Clinical Diagnosis;

Cover Clinical Diagnosis;
Clinical Diagnosis;
Charles Phillips Emerson
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Basophile Granulations (8). — These granules were originally described by Ehrlich as occurring in the mononuclear cells, especially the lymphocytes ; as not staining by dahlia, and hence differed from y granules ; and occurring especially in the cells of bone-marrow. Ehr- lich, while he has not publicly repudiated these, leads one to suppose that he now considers them to be not true granules, but nodes of the reticulum of the protoplasm.
Neutrophile Granules («). — While a somewhat similar gran
...ulation occurs in some animals, cattle, swine, and sheep (Hirsch- feld), neutrophile granules of this size, arrangement, and color are found only in man, and hence are considered by Ehrlich specific for him. They are extremely fine, dust-like, and occur in the mononu- clear cells of the bone-marrow, a few in transitional cells, and fill the ordinary finely granular cells of the blood. With the Ehrlich triple stain they take a lilac color, and this is really the only specific stain for them, but they also will take an acid stain; hence others name them the " fine oxyphilic granulation," in contradistinction to the eosinophilic or ** coarsely oxyphilic." Neusser's Perinuclear Granulation.

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