Clinical Hematology a Practical Guide to the Examination of the Blood With Refe

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Clinical Hematology a Practical Guide to the Examination of the Blood With Refe
John C Jr Da Costa
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According to Ehrlich, ^ if thorough and systematic search is made, normoblasts may be constantly found after the second or third day following the blood loss until the regeneration of the blood is complete. The transient appearance of large numbers of normoblasts, known as "blood crises, " has been already described. (See p. 189. ) Dawson, - who has carefully studied the effects of venous hemor- rhage in dogs, found no evidence of any close relation between the number of erythroblasts and the r...apidity and character of the regeneration of the hemoglobin and erythrocytes. In severe cases polychromatophiha of the erythrocytes may be noted, this sign first becoming apparent as early as the first day after the hemorrhage, and gradually disappearing as regeneration is effected. Deformities in the size and shape of the erythrocytes are not uncommon, of which microcytes constitute the most frequent example. Large hydropic megalocytes and poikilocytes are met with more rarely.
VI. LEUKEMIA.
According to the classification in general vogue Varieties, at the present time two clinical varieties of leu- kemia, the myelogenous or spleno-medullary and the lymphatic, are recognized.


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