Immunization Against Pox in Domestic Fowl

Cover Immunization Against Pox in Domestic Fowl
Immunization Against Pox in Domestic Fowl
Robert Graham
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Storage at ice-box temperature for 48 hours of 1-percent sus- pensions of fowl-pox virus containing different preservatives such as . 025 to . 5 percent formalin, . 5 percent phenol, 2 percent saponin, and . 5 percent tricresol resulted in complete loss of viability of the virus and failure to produce either a reaction or resistance to pox in four-week-old chicks.
The practical application of the foregoing findings may be stated as follows: Potent fowl- and pigeon-pox vaccines properly administ
...ered to healthy fowls produce a measurable immunity against fowl pox. The immunity induced by the application of fowl-pox vaccine, stick method, is of longer duration and better defined than the immunity induced by the application of pigeon-pox vaccine by the feather- follicle method. Pigeon-pox vaccine can be used with less risk than fowl-pox vaccine but it provides only a modified protection against the disease. In fact, fowls vaccinated with pigeon-pox vaccine may, upon subsequent ex- posure, develop lesions, but the systemic disturbance accompanying the unaltered virus infection is appreciably modified and often avoided.

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