Intestinal Auto Intoxication

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It is thus that in the physiological state the liver appears to have the same properties of fixation and reten- tion of the aromatic substances (particularly indol), as its cells isolated from the body have. It appears therefore that the liver not only transforms the aromatic bodies into less offensive matters, but that it retains a certain portion of them. Under the same head still, the liver considerably diminishes the toxicity of the substances brought to it by the portal vein.
Its power sen
...sibly lessens under the influence of intoxica- tions or disease. Herter and Wakeman have in effect shown that the absorbent power of the liver for the aromatic bodies is 78 ANTITOXIC FUNCTIONS OF THE ORGANISM notably diminished by the action of ether, chloroform or toxins. Consequently we see in diseases of the liver, in simple insuffi- ciency, in cirrhosis, the aromatic bodies indican among others increase considerably in the urine.
TOXICOLYTIC ACTION OF THE LIVER Last but not least, there remains for us to speak of the most important antitoxic action of the liver.


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