Leukaemia of the Fowl Spontaneous And Experimental

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They abound in mitotic figures. The liver cells in these foci have entirely disappeared. The small, gray nodules consist of cir- cumscribed masses of myeloid tissue, usually occupying the periportal spaces and composed of a central portion of large mononuclears sur- rounded by the mononuclear myelocyte with eosinophilic granules. In the blood-vessels and capillaries, the large mononuclear, at times, seems to greatly exceed the red blood cell in numbers.
Spleen. — Except in Nos. 31 and 7Q, the s
...pleen in every case was en- larged (Table 1) ; usually very much (Fig. 6). The dimensions, in contrast to those of the liver, are of definite comparative value. The smallest of the enlarged organs measured 3 x 2 x 1.7 cm., the largest 4 x 3 x 2.3 cm., the latter being just twice the normal in every dimension.
The weights were strikingly increased. The lowest was 6 gm., the highest, 18 gm., i. e. 18 times the normal, or .6-1.6 per cent of the body weight, i. e., 32 times the normal.
The surface of the spleen may look normal, be reddish brown and show beneath its capsule pin-point, gray Malpighian bodies.


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