Medical Chemistry Including the Outlines of Organic And Physiological Chemistr

Cover Medical Chemistry Including the Outlines of Organic And Physiological Chemistr
Medical Chemistry Including the Outlines of Organic And Physiological Chemistr
Charles Gilbert Wheeler
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Smee considers fibrin as oxidized albumen. But how can it be supposed that this oxidation takes place in a few seconds ?
Notwithstanding all that has been written concerning the probable cause of the coagulation of the blood, it must be confessed that the causes thus far assigned are not wholly satisfactory. They are, for the most part, mere hypotheses.
Serum is chiefly a solution of albumen. But this albumen is found in different states, free, and combined with soda ; also, in the analyses abo
...ve cited, the albu- minoid substances (fibrogene and fibrino-plastic sub- stance, ) which are precipitated by carbon dioxide, have been considered as albumen.
E. Mathieu and V. Urbain (9-79, 665 and 698) seem to have established, though disputed by A. Gautier (9-83-277), that the coagulation of blood is caused by the carbon dioxide, which, when blood is exposed to the air, is expelled from the blood globules, in which it is contained during life, by the oxygen of SERUM. 279 the air. Hence it is clear why alkalies and ammonium hydrate, as well as concentrated solutions of certain salts which absorb carbon dioxide, prevent the coagu- lation of blood.


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