New Hydroxamic Acids Derived From Cyclopropane Carboxylic Acid Isobutyric Acid

Cover New Hydroxamic Acids Derived From Cyclopropane Carboxylic Acid Isobutyric Acid
New Hydroxamic Acids Derived From Cyclopropane Carboxylic Acid Isobutyric Acid
Alfred Witherspoon Scott
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After evaporation of the alcohol, a viscous semi-solid mass resulted.
This mass was dissolved in water and treated with a solution of copper acetate. A grass-green copper salt of the hydroxamic acid was precipitated ; it was collected, washed thoroughly with water and dried over sulfuric acid. When the dry copper salt had been pulverized carefully, it was suspended in methanol and a stream of dry hydrogen sulfide was passed through the suspension. The solution was filtered from copper sulfide a
...nd the methanol evaporated.
The product was a yellowish crystalline material possessing an odor characteristic of impure hydroxamic acids prepared from their copper salts by this method. Upon recrystallization of it from warm ethyl acetate, pure cyclopropane-monocarboxylic hydroxamic acid was obtained; it melted at 124 with decomposition. When ligroin is 415 added to the ethyl acetate solution, some of the yellow impurity is precipitated together with a part of the hydroxamic acid.
Analyses. Subs.


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