On the Chemical Constitution of the Bile

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* * * * * The views regarding the occurrence of jaundice without retention and reabsorption of bile have totally changed since the observations of Virchow, Kuhne, and Hoppe-Leyler have shown that bile coloring matter may be formed from the free coloring matter of the blood without the action of the liver ; and e may induce artificial jaundice in animals by injecting substances we ma^ 10 PRIZE ESSAY: that dissolve the blood-corpuscles. There is now no doubt that some of the formerly enigmatical ...forms of icterus are due to the disintegration of the freed coloring matter circulating in the blood, into bile coloring matter. " Besides, the iron that both contain would point directly to a close kinship between them. It would seem, therefore, that we may finally rest upon the belief that the source of the cholepyrrhine of the bile is the ha3matin of the blood.
The resinous salts, as they are called, glyco-cholate and tauro-cho- late of soda, are, beyond question, the most important of the biliary ingredients', and form, with cholesterine, the essential constituents of the bile.


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