Paralysis And Other Diseases of the Nervous System in Childhood And Early Life

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The musele-tibres themselves seem to be altered, but no change so far lias been found in the nmscle-spindles. It may be — as (lowers has suggested — that the disease is essentially one of tlie embryonic muscular tissue; that the muscle is, so to speak, in an undeveloped condition — in a condition in which it cannot undergo develojmient, but in which it changes and atrophies, and is replaced by tibrous tissue. Certain clianges liave been described in the spinal cord, such as the presence of cavi...ties and fissures ; and it is possible that these changes may have some bearing ni)on the etiology of the condition, as showing in tiie nervous system a tendency similar to that which is ]n-esent in the muscular tissue, namely, towards the persistence of an endjryonic condition. But any definite relation of such chanufes in the cord to the muscular condition has not been demonstrateil.
Diaguosits. — The diagnosis of this disease, when one is familiar with the different varieties and the different forms in which it occurs, does not, as a rule, |)resent any very un-eat difKculties.


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