Physical Chemistry in the Service of Medicine Seven Addresses

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09 physiologist J. Loeb, and rediscovered under the most varied conditions by his numerous pupils. We can only touch upon these investigations here. That they har- monize with our own findings and represent only an ex- pression of the general principle common to them all is, however, readily discernible. The starting-point of Loeb's investigations is the question of the significance of the different ions of sea-water for the life processes of marine animals. A great similarity was found to exis...t between the effects of various ions upon phenomena of development and upon the activities of muscle and nerve.
An interesting example is furnished by the development of the eggs of Fundulus, a small bony fish. These fish are able to develop not only in sea-water but also in dis- tilled water. If immediately after fertilization these eggs are introduced into a sodium chloride solution of the concentration of the sea-water they all die in the course of a few hours without developing any further.


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