Physiological Chemistry volume 1

Cover Physiological Chemistry volume 1
Physiological Chemistry volume 1
Karl Gotthelf Lehmann
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Since leucine possesses scarcely any basic properties, the view that it is a conjugated ammonia=H 3 N. C 12 H 10 O 4 5 is the least pro- bable hypothesis regarding its theoretical composition. From Liebig's experiment, to which we have already alluded, that leucine with hydrated potash yields valerianic acid besides volatile products, no theoretical formula for this body can be provisionally deduced ; but Gerhardt and Laurent, as well as Cahours, have in part proved it to belong to the series o
...f homologous bodies with the formula C n H n+1 NO 4, to which, as we shall presently see, sarcosine and glycine pertain. But Cahours, || and subsequently Strecker, ^[ availed themselves of Piria's mode of proceeding, by which he decomposed the amide-compounds by nitric oxide (see p. 36) into water, nitrogen, and the original acid, in order to obtain the above-mentioned leucic acid from leucine. According to this view, leucine should be regarded as the amide of this acid: since H 4 NO. C 12 H U O 5 2HO = C 12 H 13 NO 4, the theoretical formula for this substance must be = H 2 N.

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