Serum And Vaccine Therapy Bacterial Therapeutics And Prophylaxis Bacterial Dia

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Serum And Vaccine Therapy Bacterial Therapeutics And Prophylaxis Bacterial Dia
Richard Tanner Hewlett
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May be given. The reaction consists of a rise of temperature above the normal of 2 F. Or more, with general malaise, and swelling, redness, desquamation, and irritability of local tuberculous lesions, such as glands and ulcers. The temperature should be taken every two hours. A rise of temperature of no more than i F. If it does not occur before or after, DIAGNOSIS OF TUBERCULOSIS IN MAN 375 and coincides with, the injection, may be considered sufficient, especially if it happens again on givin...g a slightly larger dose.
Injections of tuberculin for diagnostic pur- poses should not be made if the temperature is i F. Above normal.
2. The Cutaneous Reaction. Von Pirquet 1 observed that if the skin be scarified and a dilute solution of the old tuberculin applied, an area of redness and swelling with papulation, somewhat resembling that of vaccinia, appears in forty-eight hours in tuberculous individuals but not in non- tuberculous ones. The solution em- ployed consists of one part of the old tuberculin, one part of a 5 per cent, solution of carbolic acid in glycerine, and two parts of physiological salt solution.


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