Text book of Physiology volume 1

Cover Text book of Physiology volume 1
Text book of Physiology volume 1
Edward Sharpey Schfer
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350.
VARIA TIONS IN A CIDITY. 5 79 chemical energy of the system of mixed salts. The degree of acidity of the urine (or any analogous fluid) is in fact not an absolute quantity, but is wholly relative to the means which we employ to measure it. But by always employing the same means, be it noted, we may obtain relative results which are strictly comparable, and as an outcome of this somewhat difficult discussion, it may be suggested that we shall do well in the present state of our knowledge to
... continue to employ a simple titration method, by which we obtain comparable, if only relative, measurements. But we must employ an indicator which gives a more definite point of colour change than does litmus, and we must retain the same indicator for any one series of experiments ; moreover, the nature of the indicator used must always be stated in stating the results. Phenolphthalein, and perhaps cochineal, will serve our pur- pose. If acid urine be gradually neutralised in the presence of the former of these, which is colourless when acid, a pink tinge is developed at a certain stage in the process, and we are justified in speaking of a specimen of urine which requires more alkali to produce this change as " more acid " than one which requires less.

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