The American Journal of Anatomy

Cover The American Journal of Anatomy
The American Journal of Anatomy
Wistar Institute of Anatomy And Biology
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JACKSON with a corresponding diminishing intensity of the specific stain.
In some regions (especially in the central portion of the gland) the staining reactions may be preserved much better than else- where.
Corresponding to the cytoplasmic atrophy, there are also changes in the nucleus. That there is loss in volume (though less than in the cytoplasm) in the nucleus has already been shown by measurements. In structure, some areas may show rela- tively little nuclear change, but in the great ma
...jority of cases there is a very decided hyperchromatism (figs. 3 and 5). This is best marked in the peripheral atrophic regions above referred to, where all the nuclei may present the typical pycnotic condi- tion, shrunken, deeply staining and homogeneous. Or inter- mediate stages may occur, in which the nuclei are larger, with the chromatin dissolved into a pale-blue homogeneous matrix which obscures the nuclear network. Karyorrhexis and karyoly- sis also occur, but are comparatively rare.
In cases or areas where the atrophic changes are not so far advanced, it appears that the pycnosis first becomes evident in the nuclei of the eosinophils.


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