The Bacterial Poisons

Cover The Bacterial Poisons
The Bacterial Poisons
N F Gamalekila
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It may seem strange that these writers, when studying the chemical nature of the microbian poi- sons and finding them so closely associated with 54 albumins, had not thought to first separate the albu- mins from their cultures, leaving the microbes to vegetate in media deprived of albuminoid substances. But they had the preconceived idea that the bacterial poisons could only be formed at the expense of the albumins of the culture media. They give us no proof of this notion, so widespread and ye
...t so inexact, as we shall show later on.
But even apart from the cultures in media de- prived of albumins, there were many other means for determining the chemical nature of the bacterial poisons.
We might, for example, study what chemical changes coincide with the heating of the filtered cul- tures above 60 C. A temperature which destroys the diphtheritic poison. We offer this suggestion because Brieger and Frankel have made researches which may seem of a like nature. They have studied the non-toxic albumin produced by the emasculated diphtheria-bacillus, and found it distinguished by sev- eral constant characters from the albumin containing the diphtheria poison.


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