The Elements of the Science of Nutrition

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xiv, p. 54.
* Thiele: "Journal of Physiology," 1907, xxxvi, p. 68.
136 SCIENCE OF NUTRITION.
Friedmann^ shows that the cystin of mercapturic acid is the same cystin as may be obtained on the cleavage of protein in the laboratory.
If cystin be administered to a normal person it is burned and does not alter the normal relation between oxidized and unox- idized sulphur in the urine.^ Therefore cystin administered alone gives the same end-products as when it is administered in the protein complex.
...That cystin is the mother substance of the taurin of the bile Friedmann^ illustrates in accordance with the following formulae : c H2 SH C H2 SO3 H CH2SO3H CHNH2 + 30 = CHN H2 — CO, -= C H2 N Hj I I C OOH COOH Cystin. Cystinic acid. Taurin.
The indications are that cystin is a normal product of pro- tein metabolism which a patient suffering from cystinuria is unable to oxidize.
In a phenomenon called alcaptonuria tyrosin and phenyl- alanin are oxidized only as far as the alcaptonic acids, which are uroleucinic and homogentisic acids, and in this form they appear in the urine.


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