The Etiology of Typhus Exanthematicus

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The Etiology of Typhus Exanthematicus
Harry Plotz
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1 percent were positive. Hence we see, just as in our complement fixation work, that the agglutinins are THE ETIOLOGY OF TYPHUS EXANTHEMATICUS 29 usually absent at the height of the disease, but increase in amount at the crisis until they reach their maximum well along in the apyrexial period. In epidemic typhus Case 5, there was no agglutination four days after the crisis, but ten days later the serum agglutinated at 1 : 50. In endemic typhus Case 8, while there was a negative reaction one day... after, there was a positive reaction (1 : 200) six days after the crisis. Also in endemic typhus Case 15, a negative reaction two days after the crisis became 1 : 200 five days later.
TABLE 4 AGGLUTINATION DURING THE COURSE OF TYPHUS FEVER Case Height of Disease Crisis After Crisis (Number of days precedes result) typhus 1 Negative typhus 2 Negative 5, 1 : 100 slight Negative 3, 1: 200 + Negative 6, 1: 100 + Negative 4, negative; 14, 1: 50 + 9, 1: 100 + 3, 1: 200 + typhus 8 5, 1: 100 slight Epidem typhus 9 3, 1: 100 slight typhus 10 Negative typhus 11 4, 1 : 100 + Endem typhus 8 typhus 10 Negative Negative 1, negative; 6, 1 : 200 + 6, 1: 100 + typhus 13 7, 1: 200 + Negative Negative 2, negative; 7, 1-200 + 4, 1: 200 + 7 1- 200 4- 4, 1 : 200 + 4, 1 : 2QO + typhus 19.


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