The Influence of Animal Experimentation On Medical Science

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D. Jones. 8°, Lond. 1802.
I have been unable to find the above treatise, but the following account of the experiments is given by Travers, loc cit. p. 440.
' ' Jones ascertained, that the effusion of lymph from the wound inflicted by the ligature was sufficient, even if the ligature were removed upon the instant,, to obstruct the artery. By including a loose thread along with the artery in the ligature, he readily withdrew the latter after the infliction of the wound.
In one instance he succeed
...ed with a single ligature, and in several instances with two, three or four, made at a small distance apart. The lymph effused was in proportion to the extent of the section, or if this was incomplete, the union was equally so. He was led to conclude that the complete circular sec- tion of the internal coat was indispensable to union, and the success which attended his experiments led him to conjecture, that in some surgical cases removing the ligature as soon as it was made would be an efficient operation.

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