The Principles of Clinical Pathology; a Text-Book for Students And Physicians

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i : "Brauer, Ztft. f. phy. Chem., vol. xl. p. 182.
THE DIGESTION 281 Not infrequently the oxyhsemoglobin itself passes into the bile,® 2 even long before it appears in the urine.
Certain poisons affect the composition of the bile. Of these, we may name toluylendiamin, arseniuretted hydrogen, and phosphorus. The first two destroy the red corpuscles of the blood, but phosphorus does not do so in mammals. In the earlier stages of intoxications with these compounds, the total quantity of the bile i
...s usually diminished, the pigments are increased, and the bile salts only slightly increased or possibly diminished. Owing to an increase in its content of nucleoproteids, the bile becomes thick and viscid. In the later stages of these intoxications, the bile increases in quantity, its composition varying in different ways. These quantita- tive and qualitative changes are produced in part by the de- structive action of certain of these poisons upon the red blood-corpuscles. Yet this is not the only cause of the biliary changes.

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