The Principles of Pathological Histology

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M. F., F. M., hsematoxylin and tubercle bacillus stain.
F., or F. A., celloidin, fibrin stain.
3. Softening of the Cerebral Substance.
Embolic occlusion of a cerebral vessel leads to anaemia and death of the tissue within the area which it supplies, exactly as vascular occlusion occasions destruction of tissue in other organs (kidney, spleen).
Great caution must be exercised in the diagnosis of thrombosis in the brain as post-mortem clotting is especially common in the cerebral vessels.
Macrosc
...opically the affected tissue is recognized by the great softening it has undergone (white softening). A similar softening of the nervous tissue, espe- cially of the cord, results from post-mortem disintegration, so that a micro- scopic examination of the softened material is necessary before the intravital character of the change can Fig. 31. be recognized. Where the change has occurred intra- vitam, the softened mass contains a large number of characteristic elements, the so-called compound granule cells, or fat globule cells.

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