Digestion And Metabolism; the Physiological And Pathological Chemistry of Nutrition, for Students And Physicians

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The results of alkali therapy would without question be more certain, if all the cations are administered. It must be recalled that potassium and calcium, outside of the blood stream, outweigh sodium; especially potassium, which in some organs is present to four hundred times the amount of sodium.
The ammonia of the urine in subjects not taking alkali stands as a general index of the amount of ketonic acids. The ammonia of the normal, rarely over 0.5 gram per day, is often exceeded; the output
...may be 2 or 3 grams, 5 or 6 in severe cases, up to 10 or 12. There is no ques- tion that a high figure for ammonia is a danger signal. Each gram of ammonia represents about -6 grams of beta-oxy-butyric acid. And as the estimation of urinary ammonia is comparatively easy, the estimation of the ketonic acids may be conveniently accompHshed in this way. The action of administered alkali may also be measured in this way. When fixed alkali is given, the cation will not replace directly and at once the ammonia in molecular relations.

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