Enzymes

Cover Enzymes
Enzymes
Cohnheim, Otto, 1873-1930
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physiolog. Chem., 42 (1904). — W. W. Sawitsch: ibid., 55 (1908); 63 (1909). — M. Jacoby: Biochem. Zeitschr., i (1906).
Digitized by Google 88 ENZYMES gastric juices, gastric extract, and dried enzyme powder is always proportional. Vernon ^ noted the uniformity of rennin and trypsin in pancreatic extracts, and Pawlow and his collaborators, especially Sawitsch, were able to refute all objections. We cannot doubt to-day the identity of pepsin and rennin, but I think that we must go further than Pa
...wlow, who believed that the same enzyme-molecule has two enz)anotic actions. Hammar- sten observed that, after curdling, not all the casein is removed from the solution, but that there remains a renmant of peptone-like substance; and he suggested that, in curdling, the casein is split into two compounds.
Because all proteol)rtic enzymes aflfect casein in the same way as pepsin does, it seems to me that the best explana- tion for all the facts is that the curdling is only the first step toward the dissociation of casein.


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